| 摘要: |
| 环境内分泌干扰物(EDCs)又名环境激素,具有类似激素结构和效应,能够干扰生物体的内分泌系统,危害人类和动物健康。本文聚焦典型酚类EDCs,包括烷基酚(APs)、双酚类(BPs)和氯酚(CPs)的微生物降解研究。受污染的土壤、河流、沉积物或活性污泥中存在并可分离出能够有效降解酚类EDCs的细菌和真菌,这些降解菌在污染土壤或水体的生物原位修复以及去除废水中酚类EDCs方面具有良好的应用前景。本文系统综述了好氧和厌氧条件下酚类EDCs的降解功能菌及其降解途径,总结了酚类EDCs的降解功能酶和功能基因,包括参与羟化作用的单加氧酶和羟化酶、参与环裂解的双加氧酶和还原脱氯过程需要的还原脱卤酶等,旨在为推动酚类EDCs高效削减的微生物法技术创新提供科学依据。 |
| 关键词: 酚类内分泌干扰物，微生物降解，功能基因，烷基酚，双酚，氯酚 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| Research Progress on Microbial Degradation of Phenolic Environmental Endocrine Disruptors |
|
wu gang,zhang xu-xiang
|
| Abstract: |
| Environmental endocrine disruptors (EDCs), also known as environmental hormones, have structures and effects similar to hormones and can interfere with the endocrine systems of organisms, posing health risks to humans and animals. This paper focuses on the microbial degradation research of typical phenolic EDCs, including alkylphenols (APs), bisphenols (BPs), and chlorophenols (CPs). Bacteria and fungi capable of effectively degrading phenolic EDCs are found in contaminated soil, rivers, sediments, or activated sludge. These degrading microbes have promising applications in bioremediation of polluted soils or water bodies and in the removal of phenolic EDCs from wastewater. This paper systematically reviews the degrading microbes and their pathways under aerobic and anaerobic conditions, summarizing the degrading enzymes and functional genes involved, including monooxygenases and hydroxylases for hydroxylation, dioxygenases for ring cleavage, and reductive dehalogenases for reductive dechlorination. The aim is to provide a scientific basis for the innovation of microbial methods for the efficient reduction of phenolic EDCs. |
| Key words: phenolic endocrine disruptors, microbial degradation, functional genes, alkylphenols, bisphenols, chlorophenols |
